Are neuropsychiatric symptoms a marker of small vessel disease progression in older adults? Evidence from the Lothian Birth Cohort 1936.

Una Clancy,Ratko Radakovic,Fergus Doubal,Maria Del C Valdés Hernández,Susana Muñoz Maniega,Adele M Taylor,Janie Corley,Francesca M Chappell,Tom C Russ,Simon R Cox,Mark E Bastin,Ian J Deary,Joanna M Wardlaw

International journal of geriatric psychiatry（2023）

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摘要

Apathy independently associates with preceding longitudinal WMH progression, while depression, anxiety, and subjective memory complaints do not. Patients with apathy should be considered for enrolment to small vessel disease trials.

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关键词

ageing,apathy,cerebral small vessel disease,cognition,longitudinal studies,white matter hyperintensities

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