Cancer and brassinosteroids: Mechanisms of action, SAR and future perspectives

Marcos Lorca,David Cabezas,Ileana Araque, Andrés Terán,Santiago Hernández,Marco Mellado,Luis Espinoza,Jaime Mella

Steroids（2023）

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摘要

•Brassinosteroids (BRs) are plant hormones that stimulate their growth and resistance.•BRs have anticancer, antiviral, and antipsoriatic activity, among others.•The main anticancer mechanisms of action of BRs are reviewed and a SAR is proposed.

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关键词

BR,SAR,HSV-1,MCF-7,MDA-MB-468,LNCaP,DU-145,ER-α,ER-β,HMEC-1,CEM,HeLa,Akt,Erk1,FAK,HUVEC,AP-1,PMA,CDK,SILAC,PC-3,Bcl-2,HT-29,HCT-116,PI3K,FOXO3a,ROS,A549,AR,ULK1,MEF,Atg5,Hep G2,LXR,SCLC,VPA-17,H69,HaCaT

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