Asymptomatic Viral Presence in Early Life Precedes Recurrence of Respiratory Tract Infections.

Roy P Zuurbier,Debby Bogaert,Wouter A A de Steenhuijsen Piters,Kayleigh Arp,Mei Ling J N Chu,Elisabeth A M Sanders,Marlies A van Houten

The Pediatric infectious disease journal（2023）

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摘要

Respiratory viruses, including the seasonal human coronaviruses, are often detected in infants, and are often asymptomatic. Early life RV presence is, though negatively associated with an acute RTI, associated with future susceptibility to and recurrence of RTIs. Further studies on potential ecologic or immunologic mechanisms are needed to understand these observations.

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birth cohort study,respiratory viruses,respiratory tract infections,asymptomatic viral detection,infants

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