Next Generation Sequencing of Free Microbial DNA for Rapid Identification of Pathogens in Critically Ill Children with Systemic Inflammatory Response Syndrome (SIRS).

Sarah C Goretzki, Miriam Schäfer,Burcin Dogan,Nora Bruns,Eva Tschiedel,Peter-Michael Rath,Sebastian Voigt,Silke Grumaz, Petra Horvatek,Stefan Schönberger,Florian Stehling,Thorsten Brenner,Christian Dohna-Schwake

Frontiers in bioscience (Landmark edition)（2022）

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摘要

NGS may become a valuable addition to infectious disease diagnostics in cases of pediatric SIRS. However, NGS has not yet been validated as a diagnostic method in pediatric as a diagnostic method in pediatric patients and results should therefore be interpreted with caution. Multi-center NGS evaluation studies are currently being planned.

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关键词

SIRS,children,next generation sequencing

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