Topological disruption of high-order functional networks in cognitively preserved Parkinson's disease.
CNS neuroscience & therapeutics(2023)
摘要
This study identified disrupted topology of functional interactions at a high level with extensive alterations in topological properties and improved differentiation ability in patients with PD prior to clinical symptoms of cognitive impairment, providing complementary insights into complex neurodegeneration in PD.
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关键词
Parkinson's disease,functional connectivity,functional magnetic resonance imaging,graph theory,machine learning
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