Astragaloside IV ameliorates spinal cord injury through controlling ferroptosis in H 2 O 2 -damaged PC12 cells in vitro .

Yifei Zhou,Lin Li, Chenghuang Mao, Dongsheng Zhou

Annals of translational medicine（2022）

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摘要

The results of this investigation using the SCI cell model suggested that AS-IV alleviated SCI by promoting TFEB expression and subsequently mediating ferroptosis. This may represent a potential clinical treatment for SCI.

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关键词

Astragaloside IV (AS-IV),ferroptosis,spinal cord injury (SCI),transcription factor EB (TFEB)

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