Research progress in application of porous tantalum implant for treatment of bone defects

CAILIAO GONGCHENG-JOURNAL OF MATERIALS ENGINEERING(2022)

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摘要
tantalum metal has good biocompatibility and osteoconductivity,with a lower modulusofelasticityand a higher coefficient offriction to avoid stress-shieldingcompared with traditionalimplant metal materials.In addition,its porous structure,similarto that of human cancellous bone. Porous tantalum has received increasing attention in recent years due to its advantagesin mechanicalpropertiesandexcellentbiologicalproperties,andhasbeendevelopedand appliedinthetreatmentofvariousbonedefects. Withtheprogressofthepreparation methodsof poroustantalum materialsandtheproposalofvariousmodification methods,theprosperityofporous tantalumin clinicalapplications has beenfurther demonstrated.In thispaper,the application of porous tantalum implant in bone defects treatment was reviewed,considering its preparation technology,cytotoxicity,osseointegrationproperties,andcurrentclinicalapplications.Furthermore, the developments of porous tantalum including surface modification for establishing composite systems,optimizationofpreparationprocessesandpersonalizedpreparationtechniquesareexpectedto facilitatetheclinicalapplicationofporoustantalumimplantsinthetreatmentofbonedefects.
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关键词
porous tantalum,bone defect,bone implant,clinical application
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