Cerebrospinal fluid methylome-based liquid biopsies for accurate malignant brain neoplasm classification.

Jeffrey A Zuccato,Vikas Patil,Sheila Mansouri,Mathew Voisin,Ankur Chakravarthy,Shu Yi Shen,Farshad Nassiri,Nicholas Mikolajewicz,Mara Trifoi,Anna Skakodub,Brad Zacharia,Michael Glantz,Daniel D De Carvalho,Alireza Mansouri,Gelareh Zadeh

Neuro-oncology（2022）

引用 6|浏览41

暂无评分

摘要

CSF methylomes are reliable for liquid biopsy-based classification of the major three malignant brain tumor types. We discuss how liquid biopsies may impact brain cancer management in the future by avoiding surgical risks, classifying unbiopsiable tumors, and guiding surgical planning when resection is indicated.

查看译文

关键词

Brain cancer,DNA methylation,cerebrospinal fluid,diagnostic biomarkers,liquid biopsy

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要