Persistence of Mycobacterium tuberculosis in response to infection burden and host-induced stressors.

Trisha Parbhoo,Haiko Schurz,Jacoba M Mouton,Samantha L Sampson

Frontiers in cellular and infection microbiology（2022）

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摘要

Our results suggest that different host factors differentially impact the intracellular bacterial burden, adaptive mechanisms and entry into persistence in macrophages.

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关键词

Mycobacterium tuberculosis,bacterial heterogeneity,host-pathogen interaction,persistence,persisters,phagocytosis,phagosome acidification

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