IgG memory B cells expressing IL4R and FCER2 are associated with atopic diseases.

Carlos J Aranda,Edgar Gonzalez-Kozlova,Sean P Saunders,Weslley Fernandes-Braga,Miyo Ota,Sriram Narayanan,Jin-Shu He,Ester Del Duca,Bose Swaroop,Sacha Gnjatic, Gail Shattner,Joan Reibman, Nicholas A Soter,Emma Guttman-Yassky,Maria A Curotto de Lafaille

Allergy（2023）

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摘要

These findings suggest that CD23 IL4R IgG memory B cells transcribing IGHE are potential precursors of IgE plasma cells and are linked to pathogenic IgE production.

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关键词

IgE,atopic diseases,high-dimensional flow cytometry,memory IgG,single-cell sequencing

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