Impact of elexacaftor-tezacaftor-ivacaftor on bacterial colonization and inflammatory responses in cystic fibrosis.

Shahid Sheikh,Rodney D Britt,Nancy A Ryan-Wenger,Aiman Q Khan,Brandon W Lewis,Courtney Gushue,Hazel Ozuna,Devi Jaganathan,Karen McCoy,Benjamin T Kopp

Pediatric pulmonology（2023）

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摘要

In pwCF, ETI significantly improved clinical outcomes, reduced systemic pro-inflammatory cytokines, and restored circulating immune cell composition after 6 months of therapy.

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关键词

CFTR,cystic fibrosis,infection,inflammation

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