PD-L1 score as a prognostic biomarker in asian early-stage epidermal growth factor receptor-mutated lung cancer

European Journal of Cancer(2023)

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摘要
•PD-L1 ≥1% is an independent predictor of worse overall survival in resected epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC).•PD-L1 ≥1% is significantly associated with worse disease-free survival regardless of EGFR status.•TP53 co-mutations are more common among PD-L1 ≥1% EGFR-mutated NSCLC.•PD-L1 should be a stratification factor in adjuvant trials for EGFR-mutated NSCLC.
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关键词
PD-L1,NSCLC,EGFR,Prognostic biomarker
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