Targeted DNA sequencing to identify genetic aberrations in glioblastoma that underlie venous thromboembolism; a cohort study

Maaike Y Kapteijn,Fleur H J Kaptein,Milou A M Stals,Eva E Klaase, Inés García-Ortiz,Ronald van Eijk,Dina Ruano,Sjoerd G van Duinen,Suzanne C Cannegieter,Martin J B Taphoorn,Linda Dirven,Johan A F Koekkoek,Frederikus A Klok,Henri H Versteeg,Jeroen T Buijs

Thrombosis Research（2023）

引用 2|浏览14

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摘要

This study suggests a potential role for CDKN2A deletion in glioblastoma-related VTE. Therefore, once independently validated, CDKN2A mutational status may be a promising predictor to identify glioblastoma patients at high risk for VTE, who may benefit from thromboprophylaxis.

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关键词

Glioblastoma,Venous thromboembolism (VTE),Next-generation sequencing (NGS),Genetics,Precision medicine

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