In silico thrombectomy trials for acute ischemic stroke

Claire Miller,Praneeta Konduri,Sara Bridio,Giulia Luraghi,Nerea Arrarte Terreros,Nikki Boodt,Noor Samuels,Jose F Rodriguez Matas,Francesco Migliavacca,Hester Lingsma,Aad van der Lugt,Yvo Roos,Diederik Dippel,Henk Marquering,Charles Majoie,Alfons Hoekstra

Computer Methods and Programs in Biomedicine（2023）

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摘要

•In silico trial to evaluate treatment device performance on virtual stroke patients.•A surrogate thrombectomy model enabled in silico trials on large virtual populations.•High fibrin clots were harder to retrieve, which has also been observed in the clinic.•In silico trial compared performance of two devices on the same virtual population.

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关键词

In silico trials,Acute ischemic stroke,Computational biology,Simulation frameworks

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