Desferoxamine protects against hemophilic arthropathy through the upregulation of HIF-1α-BNIP3 mediated mitophagy

Jiamin Lin,Zhou Guo,Zehang Zheng,Liangcai Hou,Jingting Xu,Qiang Liu,Ting Du,Fengjing Guo,Xingzhi Jing

Life Sciences（2023）

引用 1|浏览3

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摘要

In conclusion, DFO could protect against HA development via HIF-1α-BNIP3 mediated mitophagy, suggesting DFO might be a potential therapeutic supplement for HA treatment.

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关键词

Hemophilic arthropathy,Desferoxamine,Iron overload,HIF-1α-BNIP3,Mitophagy

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