An Untargeted Metabolomics Approach on Carfilzomib-Induced Nephrotoxicity.

Ioanna Barla,Panagiotis Efentakis,Sofia Lamprou,Maria Gavriatopoulou,Meletios-Athanasios Dimopoulos,Evangelos Terpos,Ioanna Andreadou,Nikolaos Thomaidis,Evangelos Gikas

Molecules (Basel, Switzerland)（2022）

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摘要

Cfz causes metabolite retention in kidney and dysregulates (up and down) several metabolites associated with the occurrence of inflammation and oxidative stress.

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关键词

HRMS,carfilzomib,metabolomics,nephrotoxicity

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