A Phase 1 Trial of Highly Conformal, Hypofractionated Postprostatectomy Radiation Therapy.

Krishnan R Patel,Lindsay S Rowe,Erica Schott,Theresa Cooley-Zgela,Holly Ning,Baris Turkbey,Peter Choyke,Liza Lindenberg,Esther Mena,Peter A Pinto,Qihu Zhang,Joanna Shih,Kilian E Salerno,Deborah E Citrin

Advances in radiation oncology（2022）

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摘要

The maximum tolerated hypofractionated dose schedule for hypofractionated PORT to the prostate bed was determined to be 44.2 Gy in 10 daily fractions. The most frequent clinically significant toxicities were late grade 2+ GU toxicities, which corresponded to a worsening of late GU QoL.

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