Effect of Cuban Porcine Pulmonary Surfactant (Surfacen) and rCmPI-II Protease Inhibitor on Neutrophil Elastase Activity.

Yuliannis Lugones-Ladrón de Guevara, Mercyleidi Díaz-Reyes,Aymara Cabrera-Muñoz,Arturo Chang-Monteagudo,Alonso Del Rivero-Antigua,Odalys Blanco-Hidalgo

MEDICC review（2022）

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摘要

Surfacen and the rCmPI-II inhibitor have an anti-elastase effect on an activated neutrophil model. rCmPI-II does not affect Surfacen's interface property and, therefore, both can be evaluated for combined use in treating inflammatory lung diseases.

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关键词

Cuba,drug carriers,elastase inhibitor,neutrophils,pulmonary surfactants

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