More Efficient Complement Activation by Anti-Aquaporin-4 Compared With Anti-Myelin Oligodendrocyte Glycoprotein Antibodies.

Magdalena Lerch,Kathrin Schanda,Eliott Lafon,Reinhard Würzner,Sara Mariotto,Alessandro Dinoto,Eva Maria Wendel,Christian Lechner,Harald Hegen,Kevin Rostásy,Thomas Berger,Doris Wilflingseder,Romana Höftberger,Markus Reindl

Neurology(R) neuroimmunology & neuroinflammation（2023）

引用 7|浏览19

暂无评分

摘要

Both MOG-IgG and AQP4-IgG are able to induce CDC in a titer-dependent manner. However, AQP4-IgG showed markedly higher levels of CDC compared with MOG in vitro on target cells. This further highlights the role of complement in AQP4-IgG-mediated disease and diminishes the importance of complement activation in MOG-IgG-mediated autoimmune disease.

查看译文

关键词

anti–myelin oligodendrocyte glycoprotein,more efficient complement activation,antibodies

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要