Quantitative Susceptibility Mapping and Free Water Imaging of Substantia Nigra in Parkinson's Disease.

Dongling Zhang,Junye Yao,Junyan Sun,Qiqi Tong,Silei Zhu,Junling Wang,Lili Chen,Jinghong Ma,Hongjian He,Tao Wu

Journal of Parkinson's disease（2022）

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摘要

QSM and free water imaging have similar discriminative power in the detection of prodromal and clinical PD, while combination of these two methods increases discriminative power. Our findings suggest that the combination of QSM and free water imaging has the potential to become an imaging marker for the diagnosis of PD.

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关键词

Iron accumulation,Parkinson’s disease,free water,isotropic volume fraction,quantitative susceptibility mapping

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