SUMOylation of ERp44 enhances Ero1α ER retention contributing to the pathogenesis of obesity and insulin resistance.

Metabolism: clinical and experimental（2022）

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摘要

Our data suggest that modulation of ERp44 SUMOylation in adipocytes could be a feasible strategy against obesity and insulin resistance in clinical settings.

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关键词

Adipocyte,ER stress,Insulin resistance,Obesity,SUMOylation,Ubc9

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