Single dose topical inserts containing tenofovir alafenamide fumarate and elvitegravir provide pre- and post-exposure protection against vaginal SHIV infection in macaques.

Charles W Dobard,M Melissa Peet,Kenji Nishiura,Angela Holder,Chuong Dinh,James Mitchell,George Khalil,Yi Pan,Onkar N Singh,Timothy J McCormick,Vivek Agrahari,Pardeep Gupta,Sriramakamal Jonnalagadda,Walid Heneine,Meredith R Clark,J Gerardo García-Lerma,Gustavo F Doncel

EBioMedicine（2022）

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摘要

Funded by CDC intramural funds, an interagency agreement between CDC and USAID (USAID/CDC IAA AID-GH-T-15-00002), and by the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) through the U.S. Agency for International Development (USAID) under a Cooperative Agreement (AID-OAA-A-14-00010) with CONRAD/Eastern Virginia Medical School.

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关键词

Elvitegravir,On-demand PrEP and PEP,Tenofovir alafenamide,Vaginal inserts

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