JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRASG12C for the Treatment of Solid Tumors.
Edwige Lorthiois,Marc Gerspacher,Kim S. Beyer,Andrea Vaupel,Catherine Leblanc,Rowan Stringer,Andreas Weiss,Rainer Wilcken,Daniel A. Guthy,Andreas Lingel,Claudio Bomio-Confaglia,Rainer Machauer,Pascal Rigollier,Johannes Ottl,Dorothee Arz, Pascal Bernet, Gaelle Desjonqueres,Solene Dussauge,Malika Kazic-Legueux, Marie-Anne Lozac'h, Christophe Mura,Mickael Sorge,Milen Todorov,Nicolas Warin,Florence Zink,Hans Voshol,Frederic J. Zecri,Richard C. Sedrani,Nils Ostermann,Saskia M. Brachmann,Simona Cotesta Journal of Medicinal Chemistry(2022)
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