Spermatogonial Stem Cells and In Vitro Spermatogenesis: How Far Are We from a Human Testis on a Chip?

Christian K Ramsoomair, Charles G Alver,Ryan Flannigan,Ranjith Ramasamy,Ashutosh Agarwal

European urology focus（2022）

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摘要

An in vitro testis model will provide a superior platform for studying the testis microenvironment and molecular mechanisms that affect male fertility. The ultimate aim is to provide reproductive hope for children diagnosed with cancer who were sterilized by aggressive gonadotoxic therapies.

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