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Targeting of low ALK antigen density neuroblastoma using AND logic-gate engineered CAR-T cells

Emma Halliwell,Alice Vitali, Henrike Muller,Maria Alonso-Ferrero,Marta Barisa,Artemis Gavriil,Alice Piapi,Clara Leboreiro-Babe,Talia Gileadi,Jenny Yeung,Thomas Pataillot-Meakin,Jonathan Fisher,Lizzie Tucker,Laura Donovan,Lou Chesler,Kerry Chester,John Anderson

Cytotherapy（2023）

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摘要
These data provide further proof of concept for ALK as a neuroblastoma CAR T-cell target.
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关键词
ALK,anaplastic lymphoma kinase,CAR T cells,chimeric antigen receptor,neuroblastoma
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