Salivary Biomarker Evaluation of Chronic Pancreatitis Patients Reveals Alterations in Human Proteins, Cytokines, Prostaglandin E2 Levels, and Bacterial Diversity.

Richard T Waldron,Elaina K Jones,Vincent I Anani, Jolaine M Hines,Jing Zhao,Aurelia Lugea,Marcio A Diniz,Sungjin Kim,Aida Habtezion,Kristi L Hoffman,Joseph F Petrosino,William E Fisher,Liang Li,Ryan J Lennon,Ravinder Jit Singh,Santhi Swaroop Vege,Stephen J Pandol,Mark D Topazian

Pancreas（2022）

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摘要

Collectively, our studies identify a range of putative CP biomarkers and alterations in human saliva requiring further validation. The biomarker discovery approaches we used might lead to identification of biomarkers useful for CP diagnosis and monitoring.

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关键词

chronic pancreatitis,saliva biomarkers,quantitative proteomics,Luminex analysis of cytokines,chemokines,prostaglandin E-2,bacterial diversity

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