New pathways for drug and gene delivery to the eye: A mathematical model

•Mathematical model to describe drug delivery to the posterior segment of the eye.•Efficacy of intravitreal (IVI), suprachoroidal (SCS) and subretinal (SRS) injections enhanced by iontophoresis.•Protocols based on the use of a series of electric pulses at fixed times, can lead to an optimized SRS or SCS release.•In case of choroidal, retinal or vitreous diseases, SRS injection is the right option.