Identification of hub genes and transcription factor regulatory network for heart failure using RNA-seq data and robust rank aggregation analysis.

Dingyuan Tu,Chaoqun Ma,ZhenYu Zeng, Qiang Xu,Zhifu Guo,Xiaowei Song,Xianxian Zhao

Frontiers in cardiovascular medicine（2022）

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摘要

Our study integrated different RNA-seq datasets using RUVSeq and the RRA method and identified , , and as potential diagnostic biomarkers for HF. The results provide new insights into the underlying mechanisms and effective treatments of HF.

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关键词

RNA-seq dataset,RUVSeq,biomarker,functional enrichment analysis,heart failure,hub gene,robust rank aggregation,transcription factor

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