Evaluation of Genetic Polymorphisms of the Antioxidant Enzymes and Biomarkers of Oxidative Stress in Preterm Neonates With Respiratory Distress Syndrome Receiving External Surfactant.

Kannan Sridharan, Mona Al Jufairi, Aamal AbdulGhani Mahdi Hejab,Abdulraoof Al Madhoob,Reem Al Marzooq,Safa Taha,Muna Jaber Mulla Aljishi,Ameera Abdulhadi,Eman Al Ansari, Masooma Abdulla Ali, Maryam Ali Ahmed Naser,Ola Al Segai, Kevin Dunne

Biomarker insights（2022）

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摘要

We observed that SNPs in and significantly influence the production of oxidative stress biomarkers in preterm neonates. Baseline 8-OH-dG concentrations best predict the risk of pulmonary complications and AOPP concentrations in the umbilical cord blood predict the risk of RDS severity.

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关键词

Surfactant,glutathione S-transferase,malondialdehyde,oxidative damage,superoxide dismutase

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