High Diagnostic Accuracy of Epigenetic Imprinting Biomarkers in Thyroid Nodules.

Huixiong Xu,Yifeng Zhang,Hongxun Wu,Ning Zhou,Xing Li,John P Pineda,Yun Zhu,Huijun Fu, Ming Ying,Shufang Yang,Jiandong Bao, Lulu Yang,Bingjie Zhang,Lehang Guo,Liping Sun,Feng Lu,Hanxiang Wang,Ying Huang,Tiantong Zhu,Xiaonan Wang,Qing Wei,Chunjun Sheng,Shen Qu,Zhongwei Lv,Dong Xu, Qian Li, Yongling Dong,Jianwu Qin,Tong Cheng,Mingzhao Xing

Journal of clinical oncology : official journal of the American Society of Clinical Oncology（2023）

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摘要

This imprinting biomarker-based test can effectively distinguish malignant from benign thyroid nodules. The high PPV and NPV make the test both an excellent rule-in and rule-out diagnostic tool. With such a diagnostic performance and its technical simplicity, this novel thyroid molecular test is clinically widely applicable.

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关键词

epigenetic imprinting biomarkers,thyroid

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