Microwell culture platform maintains viability and mass of human pancreatic islets.

Hiroyuki Kato, Tatsuaki Miwa,Janine Quijano,Leonard Medrano,Jose Ortiz, Akiko Desantis,Keiko Omori, Aya Wada, Kentaro Tatsukoshi,Fouad Kandeel,Yoko Mullen,Hsun Teresa Ku,Hirotake Komatsu

Frontiers in endocrinology（2022）

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摘要

Microwell-bottomed dishes maintained viability and mass of human islets for two weeks, which is significantly improved when compared to the conventional flat-bottomed dishes.

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关键词

cell death,diabetes,human pancreatic islets,hypoxia,islet transplantation,long-term culture,microwells,type 1 diabetes

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