Elevated soluble urokinase plasminogen activator receptor is associated with renal dysfunction in a Chlorocebus atheiops COVID-19 model

Alexis A. Gonzalez, Emily L. Olsen,Stephanie Z. Killeen,Robert Blair,Surya Seshan,Edgar A. Jaimes,Chad J. Roy,Minolfa C. Prieto

JOURNAL OF MEDICAL PRIMATOLOGY（2023）

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摘要

Increases of soluble urokinase plasminogen activator receptor (suPAR) were measured in both urine and plasma of a Chlorocebus aethiops (African green monkey; AGM) mucosal infected with SARS-CoV-2. The data indicate that elevated suPAR may be associated with renal dysfunction and pathology in the context of COVID-19.

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acute kidney injury,African green monkey,nonhuman primate,renal injury,SARS-CoV-2

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