Semisynthesis, in silico study and in vitro antibacterial evaluation of fucosterol derivatives

Francisco E F da Silva, Fábio do N Ávila, Nicaely M O Pereira, Maria D de Freitas,Otília D L Pessoa,Aluísio M da Fonseca,José G M da Costa,Gilvandete M P Santiago

Steroids（2023）

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摘要

•Thirteen fucosterol derivatives were prepared.•Antibacterial activity was evaluated against Gram(+) and Gram(-) bacterial strains.•The most active compounds were investigated by molecular docking.

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关键词

Fucosterol derivatives,Lobophora variegata,Antibacterial activity,Molecular docking

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