Chemotherapy plus panitumumab/cetuximab versus chemotherapy plus bevacizumab in wild-type KRAS/RAS metastatic colorectal cancer: a meta-analysis.

Chengren Zhang,Lili Liu,Yaochun Lv,Jingjing Li,Cong Cao,Jiyong Lu,Shuai Wang,Binbin Du,Xiongfei Yang

Expert review of anticancer therapy（2022）

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摘要

Our study showed that EGFR inhibitors were superior to VEGF inhibitors in wild-type KRAS/RAS mCRC patients, especially in patients with first-line treatment. However, subsequent large sample, multi-center RCTs are needed to further verify our conclusions.

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关键词

Metastatic colorectal cancer,bevacizumab,cetuximab,chemotherapy,meta analysis,panitumumab

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