Impact of ABC (Atrial Fibrillation Better Care) pathway adherence in high-risk subgroups with atrial fibrillation: A report from the ESC-EHRA EORP-AF long-term general registry

•Patients with atrial fibrillation often suffer from other comorbidities such as chronic kidney disease, advanced age or prior thromboembolism.•These patients were treated infrequently with a holistic care approached as assessed by adherence to the ABC pathway.•ABC pathway adherence was associated with a significant reduction in the composite risk of all-cause death, thromboembolism and acute coronary syndrome.•Patients who fulfilled an increasing number of ABC criteria had a progressive improvement in long-term prognosis.