Physiological characterization and molecular identification of Saccharomycopsis fibuligera as the etiological agent of a skin lesion.
Indian journal of medical microbiology(2023)
摘要
Routine laboratory methods are not effective in identifying cryptic species resulting in the underreporting of infections caused by non-Candida yeasts. This paper presents the physiological characteristics and antifungal susceptibility of Saccharomycopsis fibuligera 12-771, isolated from a tinea-like lesion. Isolate 12-771 was identified by ITS and D1/D2 analysis as S. fibuligera. The isolate presented an auxonogram profile similar to Candida utilis, as well as protease, esterase and hemolysin activity. MICs were of 0.25 μg/mL for amphotericin B, 1-2 μg/mL for echinocandins, and 16 μg/mL for fluconazole. This work represents the first record in America of S. fibuligera as an infectious agent.
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关键词
Enzymatic activity,Saccharomycopsis fibuligera,Susceptibility,Tinea
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