In vitro alpha-amylase and alpha-glucosidase inhibitory potential of Pleurotus ostreatus cv. Florida extract

Pleurotus ostreatus cv. Florida is one of the widely used edible mushroom. The polysaccharides from this mushrooms have been studied for antidiabetic potential; however, no efforts have been made to explore the potential of this mushroom to influence carbohydrate metabolizing enzymes viz. alpha-amylase and alpha-glucosidase. The present work was undertaken to investigate the inhibitory potential of Pleurotus ostreatus cv. Florida on enzymes alpha-amylase and alpha- glucosidase. Several concentrations of extracts were used to study inhibition of enzymatic activity of alpha-amylase and alpha-glucosidase. A dose dependent inhibitory effect on enzymes was observed. The current study, for the first time, uncovered alpha-amylase and alpha- glucosidase inhibitory potential of Pleurotus ostreatus cv. Florida. The study could be helpful to isolate and characterize compounds responsible for it.