The Association Between Prebooster Vaccination Antibody Levels and the Risk of Severe Acute Respiratory Syndrome Coronavirus 2 Infection.

Noam Barda,Michal Canetti,Mayan Gilboa,Keren Asraf,Victoria Indenboim,Yael Weiss-Ottolenghi,Sharon Amit, Daniel Zubli,Ram Doolman,Ella Mendelson,Laurence S Freedman,Yitshak Kreiss,Yaniv Lustig,Gili Regev-Yochay

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2023）

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摘要

The correlation between anti-severe acute respiratory syndrome coronavirus 2 antibody levels and infection was reported. Here, we estimated the role of pre-fourth dose levels using data from 1098 healthcare workers. The risk of infection was reduced by 46% (95% confidence interval, 29%-59%) for each 10-fold increase in prebooster levels. Prebooster antibody levels could be used to optimally time boosters.

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IgG levels,SARS-CoV-2,boosters,infection risk,mRNA vaccines

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