Only Acute but Not Chronic Thrombocytopenia Protects Mice against Left Ventricular Dysfunction after Acute Myocardial Infarction.

Friedrich Reusswig,Amin Polzin,Meike Klier,Matthias Achim Dille,Aysel Ayhan,Marcel Benkhoff, Celina Lersch, Anika Prinz,Simone Gorressen,Jens Walter Fischer,Malte Kelm,Margitta Elvers

Cells（2022）

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摘要

This study discovers a novel role for platelets in cardiac remodeling and reveals that acute but not chronic thrombocytopenia protects left ventricular function post AMI.

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关键词

inflammation,myocardial infarction,platelets,remodeling,scar formation

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