Temporal lipid profiling in the progression from acute to chronic heart failure in mice and ischemic human hearts.
Atherosclerosis(2022)
摘要
Overall, a significant decreased lipidome in human ischemic LV and differential lipid metabolites in the transition of acute to chronic HF with inter-organ communication could provide novel insights into targeting integrative pathways for the early diagnosis or development of novel therapeutics to delay/prevent HF.
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关键词
Echocardiography,Heart failure,Histology,Inflammation biomarker,Lipidomics,Liquid chromatography/Mass spectrometry,Multivariate analysis
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