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Cryo-EM Reveals an Unprecedented Binding Site for NaV1.7 Inhibitors Enabling Rational Design of Potent Hybrid Inhibitors.

Marc Kschonsak,Christine C. Jao,Christopher P. Arthur,Alexis L. Rohou,Philippe Bergeron,Daniel F. Ortwine,Steven J. McKerrall,David H. Hackos,Lunbin Deng,Jun Chen,Tianbo Li,Peter S. Dragovich,Matthew Volgraf,Matthew R. Wright,Jian Payandeh,Claudio Ciferri,John C. Tellis

ELIFE（2023）

Cited 10|Views57
Key words
Nav 1,sodium channel,pain,drug discovery,cryo-EM,Human
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