Small Peptidic Ionophore for Calcium Transport.
Bioconjugate chemistry(2022)
摘要
Synthetic calcium transporters are few despite their potential biological significance. Herein, we report small alanine-derived peptides containing pyridyl-triazole motifs for inducing calcium selectivity. The peptides are decorated with hydrophobic alkyl chains to facilitate membrane insertion. The most efficient peptide scaffold has an EC value of 0.09 mol % and functions as a calcium carrier.
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关键词
small peptidic ionophore,calcium transport
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