BMSCs Promote Differentiation of Enteric Neural Precursor Cells to Maintain Neuronal Homeostasis in Mice With Enteric Nerve Injury.

Cellular and molecular gastroenterology and hepatology(2023)

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摘要
In the case of enteric nerve injury, ENPCs can differentiate into enteric neurons and glial cells to promote ENS repair and gastric motility recovery after BMSCs transplantation. BMSCs expressing GDNF enhance the migration, proliferation, and differentiation of ENPCs.
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关键词
Bone Marrow-Derived Mesenchymal Stem Cells,Enteric Nervous System,Enteric Neural Precursor Cells,Glial Cell-Derived Neurotrophic Factor
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