The Influence of Sex on Hippocampal Neurogenesis and Neurotrophic Responses on the Persistent Effects of Adolescent Intermittent Ethanol Exposure into Adulthood

Kala N Nwachukwu,Kati L Healey,H Scott Swartzwelder,S Alex Marshall

Neuroscience（2022）

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摘要

•Neurogenesis was reduced in the hippocampus of female and male rats following AIE.•AIE increased pro-inflammatory cytokines in male rats but not female rats.•AIE did not alter anti-inflammatory cytokine protein expression in either sex.•AIE did not alter neurotrophic factor protein expression in either sex.

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关键词

Adolescent Intermittent Ethanol,Neurogenesis,Hippocampus,Neurotrophic Factors,Cytokines,Sex-differences

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