The rational application of liquid biopsy based on next-generation sequencing in advanced non-small cell lung cancer.

Chenglong Zhao,Jianghua Li,Yongchang Zhang,Rui Han,Yubo Wang,Li Li,Yimin Zhang,Mengxiao Zhu,Jie Zheng,Haiwei Du,Chen Hu,Chengzhi Zhou,Nong Yang,Shangli Cai,Yong He

Cancer medicine（2023）

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摘要

CEA combined with CYFRA21-1 could effectively predict the concordance between plasma and tissue biopsies, which could be used for evaluating the priority of plasma and tissue biopsies for gene testing to timely guide clinical applications in advanced lung adenocarcinoma patients.

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关键词

circulating tumor DNA,liquid biopsy,next generation sequencing,non-small cell lung cancer,serum tumor marker

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