Nicorandil protects against coronary microembolization-induced myocardial injury by suppressing cardiomyocyte pyroptosis via the AMPK/TXNIP/NLRP3 signaling pathway.
European journal of pharmacology（2022）
摘要
Nicorandil pretreatment inhibits cardiomyocyte pyroptosis and alleviates CME-induced myocardial injury via the AMPK/TXNIP/NLRP3 signaling pathway.
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关键词
AMPK/TXNIP/NLRP3,Cardiomyocyte,Coronary microembolization,Myocardial injury,Nicorandil,Pyroptosis
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