Relationship between the tryptophan-kynurenine pathway and painful physical symptoms in patients with major depressive disorder

Yajun Yun,Qi Zhang,Wenxuan Zhao,Ting Ma,Hongzhen Fan,Luyuan Bai,Botao Ma,Siyuan Qi,Zhiren Wang,Huimei An,Fude Yang

Journal of Psychosomatic Research（2022）

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摘要

•Pain complaints are common in patients with major depressive disorder.•Tryptophan-kynurenine metabolites differed between patients and controls.•Tryptophan-kynurenine metabolite differed between patients with vs. without pain.

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关键词

Major depressive disorder,Tryptophan-kynurenine pathway,Painful physical symptoms

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