Endocrine Complications of Cystic Fibrosis
Clinics in Chest Medicine(2022)
摘要
Endocrine comorbidities have become increasingly important medical considerations as improving cystic fibrosis (CF) care increases life expectancy. Although the underlying pathophysiology of CF-related diabetes remains elusive, the use of novel technologies and therapeutics seeks to improve both CF-related outcomes and quality of life. Improvements in the overall health of those with CF have tempered concerns about pubertal delay and short stature; however, other comorbidities such as hypogonadism and bone disease are increasingly recognized. Following the introduction of highly effective modulator therapies there are many lessons to be learned about their long-term impact on endocrine comorbidities.
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关键词
Cystic fibrosis-related diabetes,Cystic fibrosis bone disease,Diabetes management,Diabetes technologies,Dual X-ray absorptiometry,Bone accrual,Body composition,Growth
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