Therapeutic activity of GARP:TGF-β1 blockade in murine primary myelofibrosis

Sara Lecomte,Julien Devreux,Grégoire de Streel,Nicolas van Baren,Violaine Havelange,David Schröder, Noora Vaherto,Christophe Vanhaver,Christophe Vanderaa, Noémie Dupuis,Christian Pecquet,Pierre G. Coulie,Stefan N. Constantinescu,Sophie Lucas

Blood（2023）

引用 2|浏览31

暂无评分

摘要

•Anti-GARP:TGF-β1 mAb exerts antitumor activity in myeloproliferative neoplasms by selectively blocking Treg-derived TGF-β1.•Targeting Treg functions is feasible and has immune-mediated therapeutic activity in blood cancers.

查看译文

关键词

primary myelofibrosis,garptgf-β1

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要