Serological Surveillance of Zoonotic Pathogens in Rats in Markets in Bogor, Indonesia.

Rats are a major carrier of several pathogens, including zoonotic pathogens that can cause fatal diseases in humans. Indonesia has one of the fastest growing populations, with high infestation of rats in urban areas. Therefore, this study aims to assess the seropositivity of zoonotic pathogens in rats from four markets in Bogor, Indonesia. A total of 80 brown rats () were captured from the markets and screened for the presence of some zoonotic pathogens, specifically hantavirus, spp., , tick-borne encephalitis virus (TBEV), and lymphocytic choriomeningitis virus (LCMV) antibodies, using indirect fluorescence assay or enzyme-linked immunosorbent assay. Among the 80 rats, 40% were seropositive for hantavirus, 36.3% for spp., 11.3% for , 6.3% for TBEV, and 0% for LCMV. Overall, these results indicate that rats in Bogor pose a potential zoonotic risk to humans.